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Gastrointestinal

News on in vitro diagnostics for gastrointestinal disease.

Mayo Clinic Spinout Developing Multiomics Blood Test to Identify Obesity Phenotypes

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The firm, Phenomix Sciences, anticipates that its test will help drive adoption of medications for obesity at a time when patients are reluctant to take them.

Active Celiac Disease Processes Informed by Intestinal Expression Comparison

A team compared expression in duodenum samples from active celiac cases, cases in remission, and unaffected controls, identifying active disease-related expression shifts.

Pancreatic, Brain Development Gene Found From Patient Exomes

By sequencing several individuals with unexplained pancreas and brain development problems, investigators identified a recurrent missense mutation in the CNOT1 gene.

Hirschsprung's Disease Genetic Analysis Reveals Mix of Common, Rare Risk Variants

Common non-coding variants, along with rarer coding alterations, appear to contribute to a developmental disease with bowel and other gastrointestinal symptoms.

Inflammatory Bowel Disease Transcriptome Analysis Finds Increased Levels of SERPINE1

Inhibiting the associated protein, PAI-1, appeared to ease inflammation and symptoms in a mouse model of inflammatory bowel disease.

The Scan

Holden Thorp to Take Over at Science

Holden Thorp is to be the new editor-in-chief of Science and its related journals.

Fewer Fish in the River

A genetic analysis of salmon scales collected over the course of a century points to a sharp decline in the number of fish returning each year to river in British Columbia, CBC reports.

Ancient DNA Lab Head Suspended During Workplace Culture Review

Adelaide University has suspended the head of an ancient DNA lab as its investigation of workplace bullying continues, Australia's ABC News reports.

PNAS Studies Describe Adipocyte Subtypes, Plant Expressome Analysis, More

In PNAS this week: gene expression profiles of adipocyte subtypes, computational approach for improving plant expressome analysis, and more.

Sep
18
Featured Webinar

Highly Sensitive Structural Variant Detection for Medical Genetics: A Comparison to the Standard of Care

Sponsored by
Bionano Genomics

This webinar will outline how a team at Radboud University Medical Center is assessing ultra-long read optical mapping on the Bionano Saphyr system to replace classical cytogenetics approaches in routine testing and for the discovery of novel structural variants with potential scientific, prognostic, or therapeutic value that are missed by standard approaches.

Oct
23
Featured Webinar

Single-Cell Methylation Profiling of Pediatric Tumors via a Unique NGS-based Approach

Sponsored by
Swift Biosciences

This webinar will illustrate how single-cell methylation sequencing can be applied to gain significant insight into epigenetic heterogeneity in disease states, advancing cancer research discoveries. 

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