Gastrointestinal

News on in vitro diagnostics for gastrointestinal disease.

In adults and children with Crohn's, miR-31 was found at higher levels in gut tissue, and the cases marked by lower expression tended to have poorer outcomes.

The companies aim to develop microbiome diagnostic assays for colon cancer and other gastrointestinal diseases including irritable bowel syndrome.

Using 16S rRNA gene sequencing, researchers detected gastric microbiome differences in people with gastric polyposis, leading to a proposed predictive model.

Genes and pathways related to mesenchymal biology, connective tissue, and conditions like obesity came to the forefront when researchers analyzed the new susceptibility loci.

Genome-wide association study hits can uncover potential therapies for conditions like inflammatory bowel disease, a Biology of Genomes speaker said.