Researchers collaborating among a number of French institutions have developed and validated a novel gene-expression signature that classifies colon cancers into six distinct molecular subtypes with different pathological characteristics and varying prognoses.

If the group can further validate the finding — published in PLOS Medicine this week — the classifier could be useful in predicting which patients are more likely to suffer recurrence after curative surgery for localized cancer and as a tool to inform more personalized treatment.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.