NEW YORK (GenomeWeb) – An international team of researchers has suggested that laminopathies, which cause rare muscle dystrophies, may actually be epigenetic disorders.

Lamin A makes up part of the nuclear lamina, which supports the inner nuclear membrane, and mutations in the lamin A/C gene can lead to muscle dystrophies like Emery-Dreifuss muscular dystrophy (EDMD). It's also thought to help in the epigenomic regulation of chromatin at the nuclear periphery through lamina-associated domains (LADs).

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