NEW YORK (GenomeWeb) – An international team of researchers has suggested that laminopathies, which cause rare muscle dystrophies, may actually be epigenetic disorders.

Lamin A makes up part of the nuclear lamina, which supports the inner nuclear membrane, and mutations in the lamin A/C gene can lead to muscle dystrophies like Emery-Dreifuss muscular dystrophy (EDMD). It's also thought to help in the epigenomic regulation of chromatin at the nuclear periphery through lamina-associated domains (LADs).

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.

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