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NEW YORK – A new epigenomic study of Clostridioides difficile has identified a highly conserved methyltransferase that may enable sporulation and could be targeted to treat infections.

C. difficile causes about half a million infections and 30,000 deaths each year and is one of the leading causes of hospital-acquired infections in the developed world. It spreads as spores, which can be resistant to many cleaning and disinfecting routines.

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