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Home » Sponsors » Advances in Spatial Genomics » 3D Architecture of Chromatin in Leukemia Affects Gene Expression

3D Architecture of Chromatin in Leukemia Affects Gene Expression

Mar 23, 2020
|
staff reporter

NEW YORK – In a study published Monday in Nature Genetics, a team led by researchers at New York University School of Medicine found that differences in three-dimensional architecture of chromatin can affect the expression of certain genes associated with leukemia.  This happens through changes to the integrity of topologically associating domains (TADs) and specific enhancer-promoter interactions.

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