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Epigenetics Research

News on epigenetic profiling, DNA methylation, histone modifications, epigenetic disorders in genetics, genomics, and molecular diagnostics.

Alzheimer's Disease Meta-Analysis Identifies Novel Differentially Methylated Loci

Combined data from six Alzheimer's studies identified differential DNA methylation in different brain regions and across the cortex.

Acute Lymphoblastic Leukemia Study Explores Role of DNA Methylation in Outcomes, Treatment

Researchers identified a patient group with hypermethylated ALL that was associated with poorer outcomes and survival.

New Algorithms Enable Direct Nanopore-Based Detection of Additional RNA Modifications
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The method was used to analyze two epigenetic modification types that were previously undetectable with Oxford Nanopore sequencing.

GWAS-Methylation Integration Could Help Identify Drug Repurposing Candidates for MS
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In research presented at the AMIA Informatics Summit, University of Texas bioinformaticians tried a new algorithm to include epigenetic factors in predicting disease progression.

Epigenetic Biomarker Firm Foxo Technologies Raises $10M

The company is developing bioinformatics and DNA microarray technologies for identifying epigenetic biomarkers of health and aging.

Apr 1, 2021

Blood Methylation Analysis, Artificial Intelligence May Detect Alzheimer's Disease Early

Mar 1, 2021

Host DNA Methylation Signatures May Predict Likelihood of Persistent, Resolving MRSA Infections

Feb 3, 2021

Human Epigenome Map Reveals New Insights Into Genetic Loci for Traits, Diseases

Jan 26, 2021

Hong Kong Team Develops Method to Improve PacBio Direct Cytosine Methylation Detection
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Dec 2, 2020

Epigenome Study Maps Hydroxymethylation Across Diverse Human Tissue Types

Nov 19, 2020

Exceptional Responders Cancer Study Points to Possible Treatment Targets
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Nov 2, 2020

Researchers Turn Methylated DNA Profiling Method Towards Prenatal Testing Applications
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Oct 16, 2020

Pancreatic Cancer Subtype With Poor Outcomes Shows Low Methylation, High Interferon Signature

Oct 14, 2020

Epigenomic Study of Brain Development Uncovers Cell Type-Specific Regulatory Programs

Sep 28, 2020

Alzheimer's Disease Linked to Epigenetic Changes in Multi-Omic Study

Sep 16, 2020

Epigenetic Markers Predict Type 2 Diabetes Patients Who Respond to, Tolerate Metformin

Sep 15, 2020

Rare Epigenetic Variation May Contribute to Genetic Disease, Large-Scale Study Finds

Aug 28, 2020

Tumor Immune Microenvironment Profiling Could Guide Therapy in Pediatric Brain Cancer

Aug 18, 2020

Increased Methylation of Memory-Related Gene May Decrease Post-Traumatic Stress Disorder Risk

Aug 3, 2020

Cervical Cancer Study in Ugandan Women Finds HPV-Specific Tumor DNA Methylation, Gene Expression

Jul 29, 2020

ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization

Jul 24, 2020

Norwegian Diagnostics Firm Age Labs to Develop Epigenetics-Based Test for SARS-CoV-2
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Jul 20, 2020

Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift

Jul 13, 2020

Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes

Jul 2, 2020

Translation of Dog Years Into Human Years Updated With Epigenetic Analysis

Breaking News
The Scan

Not as High as Hoped

The Associated Press says initial results from a trial of CureVac's SARS-CoV-2 vaccine suggests low effectiveness in preventing COVID-19.

Finding Freshwater DNA

A new research project plans to use eDNA sampling to analyze freshwater rivers across the world, the Guardian reports.

Rise in Payments

Kaiser Health News investigates the rise of payments made by medical device companies to surgeons that could be in violation of anti-kickback laws.

Nature Papers Present Ginkgo Biloba Genome Assembly, Collection of Polygenic Indexes, More

In Nature this week: a nearly complete Ginkgo biloba genome assembly, polygenic indexes for dozens of phenotypes, and more.