News on epigenetic profiling, DNA methylation, histone modifications, epigenetic disorders in genetics, genomics, and molecular diagnostics.
Researchers found that small-molecule inhibitors targeting oncogenic signal transduction or epigenetic regulation can alter specific 3D interactions in leukemia.
Previous studies that detected the presence of the N6-methyladenine bacterial DNA modification in mammalian cells were most likely contaminated.
The consortium is developing a real-time PCR test for host detection assays targeting epigenetic signatures and viral RNA for early-stage monitoring of potentially infected individuals.
Researchers identified 34 episignatures that could be used for diagnostic testing and the interpretation of ambiguous genetic test results.
Investigators tracked down a methylation signature in blood that corresponded with features found in postmortem brain samples from schizophrenia cases.
