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This Week in Science: Sep 30, 2016
In Science this week: global genetic diversity map, and more.
Germline BRCA2 Mutations Suspected in Some Primary Brain Cancer Cases
A retrospective review of panel sequencing data presented at the National Society of Genetic Counselors conference linked BRCA2 to primary brain cancer cases.
BARDA Awards $51.9M to DNAe to Develop Rapid Diagnostics
Under the contract, DNAe will develop tests for antimicrobial resistant infections and influenza that it submits to the FDA for clearance.
Frameshift plans to commercialize two applications: one for data quality control and a second for identifying mutations in rare and Mendelian disorders.
In Brief This Week: Mayo Clinic; Vela Diagnostics; MNG Laboratories; and More
A brief recap of Genetics/Genomics news the week of Sep 30, 2016: May Clinic, Vela Diagnostics, MNG Laboratories, and Rx30.
UK Bioethics Group Issues Genome Editing Report
The Nuffield Council report is the first step in addressing ethical considerations of genome editing in human health, food, and the natural environment.
Look into the (Possible) Future
In a blog post, Brigham and Women's Hospital's Robert Green discusses "predispositional personal genome sequencing."
Urged to Amend
Stat News reports that there's muted opposition to the Kuwaiti DNA database law.
Premaitha Revenues Up on Sales of Iona Prenatal Screening Test
Premaitha said it has sold more than 17,000 of the tests, which is the focus of an ongoing patent-infringement suit, since its launch in early 2015.
To Follow Up On
The Nuffield Council on Bioethics identifies ethical questions to explore surrounding genome editing.
Recently presented studies support the utility of Genestrat and Veristrat for detecting actionable mutations and guiding therapy in drug-resistant lung cancer patients.
Tute Genomics Suspends Kickstarter Campaign Following FDA Letter
The company has decided to put its direct-to-consumer sequencing campaign on hold after receiving a letter from the FDA.
ReadCoor is currently using its its technology to map neural circuits in the brain and has projects in the pipeline related to oncology and infectious disease.
During a live webcast, CTO Clive Brown provided an update on the company's development plans and upcoming updates.
Expanded Carrier Screening in Egg, Sperm Donors Raises New Issues, Genetic Counselors Find
Participants of the National Society of Genetic Counselors annual education conference highlighted the need for consensus guidelines for screening potential gamete donors.
DNAStar Lasergene 14
DNAStar has launched Lasergene 14 software. The update includes three new applications: GenVision Pro, a comprehensive genome browser; NovaDock, a protein-protein docking application; and NovaFold Antibody, a specific antibody structure prediction program. It also includes enhancements to virtual cloning with three new cloning methods, newly integrated combined next-generation sequencing workflows, enhancements to the de novo transcriptome workflow introduced with Lasergene 13, and a workflow in support of Sanger validation of NGS data, the company said.
House, Senate Leaders Aim to Pass 21st Century Cures Bill by Year End
The bill, which would boost NIH funding among other things, was overwhelmingly approved by the House and cleared a Senate subcommittee, but has stalled amid negotiations over appropriations.
Some Cold Water
Even with all the current enthusiasm for gene therapies, Tech Review cautions that they are mostly in the early stages of development.
Charles River Laboratories to Offer PathoQuest Viral Safety Testing Service
The service combines PathoQuest's proprietary curated virus database with an automatic analysis pipeline to identify viral contaminants in biological products.
Global Map of Amphibian, Land Mammal Genetic Diversity Reveals Impact of Human Habitation
A University of Copenhagen-led team found that regions with high levels of human activity harbor lower levels of amphibian genetic diversity.
DuPont Inks CRISPR/Cas9 Deal With International Maize and Wheat Improvement Center
DuPont Pioneer has entered into a collaboration to apply CRISPR genome editing to the development of crop varieties for farmers in developing countries.
Two Broad Institute teams, led by Eric Lander and Feng Zhang, respectively, have published new papers today in Science on new uses for lenti-CRISPR screens.
Agilent Technologies, Burning Rock Collaborate on Cancer Diagnostics for China
China-based Burning Rock will develop cancer diagnostics for Chinese patients based on the Agilent SureSelect target enrichment system.