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University of Florida Team Reports on Cancer Screening Microarray
The microarray facilitates drug screening in cancer stem cells and other rare cell populations.
'Pushing Boundaries'
The New York Times examines ethics and China's push to lead biomedical research.
Nuclea, Aelan Ink Biomarker Test, Companion Dx Deal
The arrangement will join Nuclea's expertise in proteomics with Aelan's genomics know-how.
Appeals Court Upholds Rejection of New England Biolabs Suit Against Enzymatics
The appeals court agreed with a previous ruling that found New England Biolabs failed to file its lawsuit in a timely manner.
Allscripts Makes $200M Investment in NantHealth
The partners are working to integrate NantHealth's Genomic Proteomic Sequencing and Eviti cancer treatment planning platform with Allscripts' software.
Medison Pharma to Distribute GenomeDx Prostate Cancer Test in Israel, Palestine
The test is designed to predict prostate cancer aggressiveness and launched in the US in 2013.
Hints of Freshly Mown Grass and Parchment
Researchers report that what scents someone picks up can reflect their complement of immune genes.
Picking up Protease Allowed Y. Pestis to Cause Pneumonic Plague, Study Finds
A later change in the protease gene likely enabled the bacterium to cause the invasive infection of bubonic plague.
ImmunArray is launching the SLE-Key Rule Out test to exclude a diagnosis of lupus, a test run on its multiple-antigen microarray-based technology.
Experts at Vanderbilt discussed future expansion of its PREDICT program, and provided a glimpse at how doctors have responded to genomic information in EMRs.
Consortium Describes Ancestry Patterns in Brazilian Populations
Using genome sequencing data on 30 Brazilians and genotyping information on almost 6,500 more, the Brazilian EPIGEN Project Consortium considered ancestry and admixture patterns in three parts of Brazil.
All the Funding Rates
At her blog, Sally Rockey dives into National Institutes of Health funding data.
Ceres Receives $746K from Gates Foundation for TB Test Development
Intended for diagnosing active pulmonary tuberculosis, the test will use Cere's Nanotrap reagents for enriching target analytes for downstream analysis.
ENCODE Effort to Use DNAnexus Data-Sharing, Analysis Platform
DNAnexus' platform will support data analysis and sharing for the third phase of the Encyclopedia of DNA Elements project.
This Week in PNAS: Jun 30, 2015
In PNAS this week: ancestry and admixture in Brazilians, characterization of novel double-stranded RNA mycovirus, and more.
Exome Sequencing Uncovers New Monogenic Form of Obesity
Researchers detected a truncating mutation in the carboxypeptidase E gene in members of a Sudanese family affected by extreme obesity, glucose metabolism problems, and other symptoms.
10X Genomics GemCode Platform
10X Genomics has started shipping the GemCode platform for generating long range genomic information from short read sequencing data. The platform consists of instrumentation, reagents, and software and generates so-called Linked-Reads that deliver haplotype phasing, structural variation, and other genomic information. GemCode, which requires 1 nanogram of input DNA, partitions arbitrarily long DNA molecules and prepares multiple barcoded sequencing libraries in parallel. 10X Genomics previewed the product earlier this year at the Advances in Genome Biology and Technology conference.
Exiqon ExiLERATE LNA
Exiqon has launched a quantitative PCR product portfolio, ExiLERATE LNA, enabling real-time PCR analysis of mRNAs and long non-coding RNA. The suite of products supports sample isolation, cDNA generation, real-time PCR amplification, and detection, and is compatible with all major real-time PCR instruments. It includes endogenous controls and supports custom assay design facilitated by an assay design tool called XploreRNA.
CRISPR Excitement
Researchers and drug developers are excited about the potential of CRISPR-Cas9-based therapeutics, the Wall Street Journal reports.
Link Technologies Adds Japanese Distributors Cosmo Bio and Shigematsu
The reagent supplier now has three Japanese distributors following a 2013 deal with GeneDesign as a representative throughout that country.
Just Another Mitochondrial Genome
An editorial appearing at The Scientist bemoans the high numbers of mitochondrial genome papers and suggests a different path for mitochondrial genome research.
Study Shows Genetic Support for Drug Targets Could Double Clinical Development Success Rate
Therapies aimed at drug targets that have been linked genetically to disease fare better through the drug development pipeline, researchers from GSK and elsewhere found.
Researchers Combine Single-Molecule Sequencing, Mapping Technologies to Analyze Human Genome
A Mount Sinai-led team of researchers combined the technologies to generate de novo assemblies and get a better view of structural variations.
Through its agreement with Quest Diagnostics, the company plans to launch a BRCA1/2 test, followed by tests for Lynch syndrome and HPV.
This Week in PLOS: Jun 29, 2015
In PLOS this week: genomic analysis of Malaysian tuberculosis strain, database of bat genomes, and more.