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University of California Files Suit Against Genia Cofounder
The university claims that Genia's patents are based on technology that was developed by UCSC researchers and that UCSC should have ownership of them.
Myriad Disputes Research, Reasoning Underpinning Medicare Proposal to End Vectra DA Coverage
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Contractor Palmetto GBA issued a draft local coverage determination proposing ending coverage of the test based on factors including a recent critical study.
Top 10 Articles on GenomeWeb in 2016
Oh, Turn It Off
Researchers uncover anti-CRISPR proteins that could help genetic engineering to be safer.
FDA's Device Center Publishes 2017 Priorities for Guidances
The annual list includes guidelines that would clarify regulations for garnering premarket approval or clearance of devices and diagnostics, particularly next-generation sequencing tests.
Efforts to Boost Minority Numbers in Clinical Trials
Researchers try to increase numbers of minorities in cancer immunotherapy trials, the New York Times reports.
The Big Ones of 2016
The biggest biology stories of the year include the Zika virus, CRISPR, and more, according to Wired.
FANCM Mutations Linked to Early-Onset Familial Breast Cancer
A team of German researchers reported that loss-of-function mutations in FANCM were more common among cases that developed the disease at a young age.
The researchers found that whole-genome amplification can create technical artifacts in sequence data that appear as loss-of-function indels.
A New Phage or Two
Two high school students in Kentucky uncovered novel bacteriophages as part of a genomics class, the Kentucky New Era reports.
GeneNews Truncates Offering Due to Market Conditions
The Toronto company raised C$721,000 of its previously announced offering that targeted up to C$3 million.
This Week in Nature: Dec 29, 2016
In Nature this week: European ash tree genome sequencing, and more.
The Alt-Right and Genetic Ancestry Testing
The Atlantic writes that white nationalists are interested in genetic ancestry testing.
Younger, Older Prostate Cancer Cases Marked by Distinct Expression Patterns
In individuals diagnosed with prostate cancer before the age of 45, researchers saw enhanced expression of immune- and inflammation-related genes.
Pairnomix's First Patient Report Makes Case for Painstaking Individualized Medicine Approach
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The results begin to adress questions about whether the company's meticulous, but costly research services can actually impact patient outcomes.
The law contains provisions that proponents say will advance precision medicine and speed new tests to market, but critics worry if this will come at a cost to public health.
UCSF Team Describes Anti-CRISPR/Cas9 Proteins
Derived from Listeria phages, the study found four new proteins that inhibit Cas9 activity, two of which also work in E. coli and engineered human cells.
The researchers found preliminary evidence that some inherited cancer mutations may be more or less common in African-American women than Caucasian women.
The partners have opened a new biorepository that will engage with clinical researchers and foster future personalized medicine efforts in the German capital.
App for the Whole Lab
Some research labs are turning to group messaging apps to communicate, according to Nature News.
This Week in Genome Biology: Dec 28, 2016
In Genome Biology this week: 4C-seq to examine chromatin patterns in IBD, Iberian lynx demographic patterns, and more.
Trading and Legislating
The Wall Street Journal says President-elect Donald Trump's pick to lead the Department of Health and Human Services traded medical company stock while supporting legislation affecting such firms.
Myriad Inks $300M Credit Agreement
The company borrowed $205 million in revolving loans from the credit facility, which matures on December 23, 2021.
Variation Lost
A writer argues that gene editing might eliminate variants that are beneficial in some circumstances, the Telegraph reports.
Endometrial Cancer Mutations Detected in Uterine Lavage Samples
A team from Mount Sinai and Swift Biosciences used targeted sequencing to detect cancer mutations in uterine lavage fluid.