Started by three UC Berkeley dropouts and fresh off a $28 million Series A, LatchBio seeks to bridge the gap between biologists and bioinformaticians with its software ecosystem.
A prospective, multicenter study involving 345 children or young adults with cancer suggested tumor panel sequencing can help guide treatment, improve diagnoses, or inform prognoses.
The center is leading a group that hopes to generate whole-genome sequencing data for psychiatric patients from a large, existing New York state clinical database.
An algorithm developed in Aviv Regev's lab and an algorithm developed for Fei Chen's Slide-seq were among the top performers, the study authors said.
The analysis also uncovered a set of activated fibroblasts within a subset of DCM and HCM samples that were not present among non-failing hearts.
The institute established the Women's Genetic Center with Columbia University and is test-driving Ultima Genomics' new sequencer to reduce WGS cost.
Researchers suggest work is needed to address issues like batch effects and missing protein values as well as to tie single-cell data to biological insights.
The firm envisions marketing the 53-gene signature with its existing MammaPrint and BluePrint tests as a comprehensive platform for breast cancer treatment selection.
Namocell offers Pala, a two-laser system with up to 11 fluorescent detection channels, and Hana, a single-laser system with two fluorescent detection channels.
A phenome-wide association study focused on microbiome-associated variants led to conditions ranging from skin disease to diabetes, heart disease, or multiple sclerosis.
These changes could potentially be used to identify polyps that are further along the progression pathway to malignancy.
Using a computational method called Dig, researchers traced mutation rates in 37 cancer types, focusing on suspected driver mutations under positive selection across the genome.
The firms aim to improve the resolution and efficiency of single-cell RNA sequencing (scRNA-seq) analysis of rare cell populations.
Researchers uncovered differences in the brain cell types found among worker, queen, male, or unfertilized gyne ants.
Using genetic, epigenetic, expression, and other data, researchers narrowed in on genes, pathways, and cell types involved in kidney disease.
Rady Children's Institute for Genomic Medicine Partners With Inozyme Pharma on NGS Newborn Screening
Rady has begun a pilot program to evaluate WGS-based screening for approximately 400 rare genetic diseases as a supplement to existing newborn screening.
Multiple presentations at the recent ESHG meeting focused on questions related to diversity in GWAS as well as applying risk scores in admixed populations.
The Human Immune System Explorer is meant to automate research pipelines and facilitate data sharing for longitudinal studies including for long COVID.
Investigators identified up to 21 copy number signatures in cross-cancer analyses, including potential disease response markers and signatures linked to chromosomal instability features.
The Netherlands nonprofit has developed a fully automated cancer WGS data curation pipeline and is providing a cancer diagnostic service to hospitals.
Investigators shared results of a study this week in which ctDNA residual disease testing gave advance notice of late recurrences in surgically resected HR+ HER2- patients.
The companies hope to make single-cell spatial omics data from the Rebus Esper system accessible for researchers without a deep bioinformatics background.
Researchers reported prospective randomized trial data showing non-inferiority of adjuvant treatment guided by minimal residual disease testing.
The three-way strategic partnership aims to develop a spatial multiomics pipeline to foster further regional collaborations.