UK Team Shows That Schizophrenia, Bipolar Disorder, Share Genetic Roots | GenomeWeb

A team of British researchers has shown that schizophrenia and bipolar disorder share genetic roots that stem from reduced expression of genes responsible for myelin development.

Sabine Bahn from the University of Cambridge, UK, and colleagues investigated oligodendrocyte-specific and myelination-associated gene expression in schizophrenia and bipolar disorder. (Oligodendrocytes produce the myelin sheaths, which insulate nerve cells. Myelin, which is 80 percent lipid and 20 percent protein, enables electrical impulses to travel down the axon.)

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