UCSF, Cold Spring Harbor Laboratories | GenomeWeb

UCSF Researchers Identify Gene Family, Mutation Tied to Longevity

Researchers at the University of California, San Francisco, have identified around 200 genes and other biological systems that are believed to double the life span of C. elegans.

The researchers found that a single “life-extending mutation” in the daf-2 gene exerts its influence through antimicrobial and metabolic genes, through genes controlling the cellular stress response, and by dampening the activity of specific life-shortening genes.

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