Skip to main content
Premium Trial:

Request an Annual Quote

TrimGen Gets FDA OK for Warfarin Genotyping Test

NEW YORK (GenomeWeb News) – TrimGen has received US Food and Drug Administration 510(k) clearance for its eQ-PCR Warfarin Genotyping kit, the Sparks, Md.-based firm said today.

The TrimGen kit tests for SNPs in the VKORC1 and cytochrome P450 CYP2C9 genes, which serve as clinically relevant predictors of warfarin dosing. The assay is used aid physicians in identifying patients who may be at risk of warfarin sensitivity.

TrimGen is one of several firms over the past year and a half to receive FDA clearance for a warfarin sensitivity test, following Nanosphere, Autogenomics, ParagonDx, and Osmetech.

The Scan

Wolf Howl Responses Offer Look at Vocal Behavior-Related Selection in Dogs

In dozens of domestic dogs listening to wolf vocalizations, researchers in Communication Biology see responses varying with age, sex, reproductive status, and a breed's evolutionary distance from wolves.

Facial Imaging-Based Genetic Diagnoses Appears to Get Boost With Three-Dimensional Approach

With data for more than 1,900 individuals affected by a range of genetic conditions, researchers compared facial phenotype-based diagnoses informed by 2D or 3D images in the European Journal of Human Genetics.

Survey Suggests Multigene Cancer Panel VUS Reporting May Vary Across Genetic Counselors

Investigators surveyed dozens of genetic counselors working in clinical or laboratory settings, uncovering attitudes around VUS reporting after multigene cancer panel testing in the Journal of Genetic Counseling.

Study Points to Tuberculosis Protection by Gaucher Disease Mutation

A mutation linked to Gaucher disease in the Ashkenazi Jewish population appears to boost Mycobacterium tuberculosis resistance in a zebrafish model of the lysosomal storage condition, a new PNAS study finds.