Toronto, Canada-based Tm Bioscience has had a recent string of successes licensing its Tag-It reagents, especially its cystic fibrosis panel, but investors have yet to notice the company, which trades on the Toronto Stock Exchange.

"I think the market is really flat, and I think Tm is caught up in that," Greg Hines, Tm CEO, told Pharmacogenomics Reporter this week. "There are a lot of negative things that have been going on in the [Canadian] biotech sector."

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While gene therapies may have high price tags, they could be cheaper than the cost of managing disease, according to MIT's Technology Review.

Researchers are looking for markers that indicate which cancer patients may respond to immunotherapies, the Associated Press writes.

In Nature this week: paternal age associated with de novo mutations in children, and more.

Nature News writes that researchers are still wrangling over the role of the p-value.