Sloan Kettering Research May Help Eliminate Non-Responders from Iressa, Tarceva Patients | GenomeWeb

Another small piece of the Iressa puzzle may have been fitted into place by Memorial Sloan Kettering Cancer Center researchers who seem to have found a way to identify some non-responding patients.

The study, which appears in the current issue of the online journal Public Library of Science Medicine, examines the effect of mutations in the KRAS or EGFR genes on non-small cell lung-cancer patient survival. The two genes produce proteins that function in the same signaling pathway.

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