Should Gene Expression-Based Prognostics Require More Patient Training Samples? | GenomeWeb

Prognostic tests such as Genomic Health's Oncotype Dx and Agendia's MammaPrint should be constructed using many more patient samples if they are to reach expected levels of reproducibility and test-to-test comparability, according to a recent study.

Moreover, one of the study authors said he believes regulatory bodies should develop requirements for the size of patient-sample populations for prognostic tests based on gene expression.

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