US Patent 7,115,726. Haplotype structures of chromosome 21. Inventors: David Cox, Deana Arnold. Assignee: Perlegen Sciences.
The invention “includes the use of any of the polymorphisms, SNP haplotype blocks or SNP haplotype patterns,” according to the patent abstract. In one embodiment, “susceptibility to a phenotype resulting from an allele or marker in linkage disequilibrium with such polymorphic forms is evaluated.” Novel therapeutic and diagnostic compounds and methods are also disclosed.

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