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Qiagen, SuperArray Bioscience, Affymetrix, Spectral Genomics


Qiagen has launched its Peach Fruit Genome Oligo set for the peach fruit genome. The oligo set, which contains 4,806 70-mer probes, relies on publicly available sequences from several international peach genomics programs. Sequences were also derived from the work of the ESTree Consortium.

The company also released an oligo set for the genome of the marine bacterium Pirellula (Rhodopirellula baltica [Pirellula sp. strain 1]). The oligo set contains 7,353 70-mer probes representing the complete genetic potential of the bacterium. R. baltica belongs to the Planctomycetales order, and is the first member of this order to be completely sequenced, said Qiagen.

Qiagen used publicly available sequence data from the REGX-Project to design the probes.

Qiagen later this year plans to release a Tomato Genome Oligo Set and Potato Genome Oligo Set.

SuperArray Bioscience has rolled out the Human Hematology and Human Cancer arrays, the first two products in its new line of pathway-specific Oligo GEArray Focused DNA Microarrays.

The 60-mer array systems rely on chemiluminescence detection and a one-tube labeling method. The Oligo GEArray’s gene content can be customized for at least $100 per array, the company said.

Affymetrix has released its GeneChip Mapping 10K version 2.0, and the widely expected Mapping 100K array set. The new 10K appears one year after the first version was released. The 100K, meantime, has been tested at 27 academic and industry labs since December 2003. Affy said the Novartis Institutes for Biomedical Research, Myriad Genetics, the National Cancer Institute, the Mayo Clinic, the Max Delbruck Center, and the Cancer Genome Project at the Wellcome Trust Sanger Institute are customers [see 9/11/03 PGx Reporter].

Spectral Genomics has launched its Constitutional Chip version 1.0 for comparative genomic hybridization. The Constitutional array contains 464 BAC clones associated with “constitutional” analysis of 41 known genetic syndromes and telomere abnormalities, and can detect single copy number changes.

The chip contains clones believed to be associated with pre-natal and post-natal analysis of genetic defects based on established practices including trisomy 21, trisomy 18, Wolf Hirshorn Syndrome, DiGeorge Syndrome and Cri du Chat Syndrome.

The chip also includes spots representing negative controls, calibration controls for standardization of detection, and clones not likely to be affected by genetic defects that form the base line for detection.

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