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Population Genetics Gets $1.2M Award to Partner with Cardiff U on AD Study

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – UK next-generation sequencing sample prep firm Population Genetics Technologies today said it has been awarded $1.2 million to collaborate with Cardiff University in Wales on a large scale two-year study of genetic predisposition to Alzheimer's disease.

The Translation Award is being given by the Wellcome Trust.

Population Genetics will screen Alzheimer's patients for specific genes that were identified by Cardiff University and its fellow collaborators in recent large scale genome-wide analyses of common genetic variants. DNA samples from populations of Alzheimer's have been chosen for the study by Julie Williams, a professor in the department of psychological medicine and neurology at the university, and a member of the school's MRC Centre for Neuropsychiatric Genetics and Genomics.

The research will be directed at genetic regions involving pathways believed to be involved in the disease's pathology, and the results are expected to validate Population Genetics' methods and to provide Cardiff University information about previously undetected rare genetic variants, Population Genetics said in a statement.

According to the Cambridge, UK company its technologies reduce "dramatically" the costs of doing large-scale population studies on next-generation sequencing platforms, while enabling the detection and characterization of rare allelic variations in disease phenotypes.