Pfizer Submits Crizotinib NDA with FDA; Abbott to File Companion Dx Approval Application Soon | GenomeWeb

Pfizer this week announced that it had filed a new drug application with the US Food and Drug Administration for the pharmacogenomically guided non-small cell lung cancer drug crizotinib.

The company is seeking approval for crizotinib in advanced NSCLC patients whose tumors harbor the EML4 and ALK fusion oncogene, and as such a genetic test needs to be marketed with the drug to pick out patients expressing this gene marker.

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