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Pairings: Nov 10, 2010

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Foundation Medicine, an oncology-focused personalized medicine firm that launched in April, announced the appointment of Maureen Cronin to the newly created position of senior vice president of research and product development. In this role, Cronin will lead the development and advancement of Foundation's personalized cancer treatment tests.

Cronin joins Foundation from Genomic Health, where she spent nine years leading research and product development efforts in molecular diagnostics and oncology personalized medicine.

The Scan

Study Finds Sorghum Genetic Loci Influencing Composition, Function of Human Gut Microbes

Focusing on microbes found in the human gut microbiome, researchers in Nature Communications identified 10 sorghum loci that appear to influence the microbial taxa or microbial metabolite features.

Treatment Costs May Not Coincide With R&D Investment, Study Suggests

Researchers in JAMA Network Open did not find an association between ultimate treatment costs and investments in a drug when they analyzed available data on 60 approved drugs.

Sleep-Related Variants Show Low Penetrance in Large Population Analysis

A limited number of variants had documented sleep effects in an investigation in PLOS Genetics of 10 genes with reported sleep ties in nearly 192,000 participants in four population studies.

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.