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Pairings: Apr 27, 2011


Sera Prognostics said that it has hired Mark Ostrowski to lead the company's management team as president and CEO, and that board member Gregory Critchfield will expand his role and become executive chairman.

Both of these positions previously were held by company co-Founder Dennis Farrar. Critchfield was president of Myriad Genetics Laboratories for a dozen years, and Ostrowski served in management positions at Dianon Systems, Myriad Genetics, and Perlegen.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.