Oxford Gene Technology has extended its Chip2 family of ChIP-on-chip microarray products with the addition of four prokaryote species. These include Escherichia coli 0157, Salmonella typhimurium LT2, S. typhimurium SL1344, and Streptomyces coelicolor.
The Chip2 microarrays can be used to identify the binding positions of global DNA-binding proteins, analyze changes in a particular protein’s binding under “various environmental conditions,” or to reveal potential therapeutic targets against a prokaryotic species.
Each Chip2 microarray is fabricated using OGT’s ink-jet in situ synthesis platform and interrogates the genome of interest with a probe density of 22,000 oligonucleotide features.
ChIP microarray data generated can then be analyzed in relation to its relative gene position using an OGT-developed ChIP browser.