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NIH Grants for Pharmacogenomics Research FY 06 May 14 -- June 20*

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NIH Grants for Pharmacogenomics Research FY'06
May 14 — June 20*
City, State, or Country Name
Organization Name
Principal Investigator
Award
Title
Alabama
Birmingham
University of Alabama
at Birmingham
Bridges, S
$24,386
Predictors of treatment response in early aggressive RA
California
Los Angeles
University of California
Los Angeles
Wong, Ma-Li
$148,281
Pharmacogenetics of antidepressant drugs
Florida
Gainesville
University of Florida Johnson, Julie
$125,319
Beta-receptors and cardiovascular pharmacogenomics
Tampa H. Lee Moffitt Cancer Center and Research Institute Sebti, Said
$295,378
Targeted intervention of breast oncogenic pathways
H. Lee Moffitt Cancer Center and Research Institute Lancaster, Johnathon
$66,015
Gene expression profiles to predict ovarian cancer chemo-response in the elderly
Indiana
Indianapolis
Purdue University at Indianapolis Flockhart, David
$142,366
Clinical relevance of cytochrome P450 pharmacogenetics
Optosonics Krueger, Robert
$754,104
In vivo thermoacoustic imaging of HER2 status
Illinois
Chicago
University of Chicago Gershon, Elliot
$372,291
Multidiciplinary psychiatric genetics training program
University of Chicago Phan, K. Luan
$171,612
Neuro-Genetic markers of SSRI treatment response in social anxiety disorder
Kansas
Kansas City
University of Kansas Medical Center Wan, Yu-Jui
$345,095
Alcohol pharmacogenetics in Mexican Americans
Maryland
Baltimore
Johns Hopkins University Messersmith, Wells
$290,139
Evaluation of BAY43-9006/Cetuximab in colorectal cancer
Massachusets
Boston
Dana-Farber Cancer Institute Silverman, Lewis
$164,150
Pharmacogenetics of asparaginase-induced pancreatitis
Massachusets General Hospital Settleman, Jeffery
$354,904
Gefitinib-sensitive EGF receptor mutants in lung cancer
Missouri
St. Louis
University of Missouri St. Louis Wong, Chung
$55,248
Computer-aided design of anti-cancer drugs targeting protein kinases
Washington University Ellis, Matthew
$511,683
Novel biomarkers for aromatase inhibitor therapy
New York
Bronx
Montefiore Medical Center Gallagher, Robert
$341,270
Assessment of clinical retinoid activity in leukemia
Pennsylvania
Pittsburgh
University of Pittsburgh Li, Song
$358,613
Pharmacogenetic therapy of pulmonary hypertension
Utah
Salt Lake City
University of Utah Yost, Garold
$290,030
Cytochrome P450 gene regulation in lung
*SOURCE: US National Institutes of Health

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The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.