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NIH Grants for Pharmacogenomics Research FY 06 May 14 -- June 20*

NIH Grants for Pharmacogenomics Research FY'06
May 14 — June 20*
City, State, or Country Name
Organization Name
Principal Investigator
University of Alabama
at Birmingham
Bridges, S
Predictors of treatment response in early aggressive RA
Los Angeles
University of California
Los Angeles
Wong, Ma-Li
Pharmacogenetics of antidepressant drugs
University of Florida Johnson, Julie
Beta-receptors and cardiovascular pharmacogenomics
Tampa H. Lee Moffitt Cancer Center and Research Institute Sebti, Said
Targeted intervention of breast oncogenic pathways
H. Lee Moffitt Cancer Center and Research Institute Lancaster, Johnathon
Gene expression profiles to predict ovarian cancer chemo-response in the elderly
Purdue University at Indianapolis Flockhart, David
Clinical relevance of cytochrome P450 pharmacogenetics
Optosonics Krueger, Robert
In vivo thermoacoustic imaging of HER2 status
University of Chicago Gershon, Elliot
Multidiciplinary psychiatric genetics training program
University of Chicago Phan, K. Luan
Neuro-Genetic markers of SSRI treatment response in social anxiety disorder
Kansas City
University of Kansas Medical Center Wan, Yu-Jui
Alcohol pharmacogenetics in Mexican Americans
Johns Hopkins University Messersmith, Wells
Evaluation of BAY43-9006/Cetuximab in colorectal cancer
Dana-Farber Cancer Institute Silverman, Lewis
Pharmacogenetics of asparaginase-induced pancreatitis
Massachusets General Hospital Settleman, Jeffery
Gefitinib-sensitive EGF receptor mutants in lung cancer
St. Louis
University of Missouri St. Louis Wong, Chung
Computer-aided design of anti-cancer drugs targeting protein kinases
Washington University Ellis, Matthew
Novel biomarkers for aromatase inhibitor therapy
New York
Montefiore Medical Center Gallagher, Robert
Assessment of clinical retinoid activity in leukemia
University of Pittsburgh Li, Song
Pharmacogenetic therapy of pulmonary hypertension
Salt Lake City
University of Utah Yost, Garold
Cytochrome P450 gene regulation in lung
*SOURCE: US National Institutes of Health

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The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.