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NIH Grants for Pharmacogenomics Research FY 06 Jan. 16 -- Feb. 12*

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NIH Grants for Pharmacogenomics Research FY'06
Jan. 16 — Feb. 12
City, State, or Country Name
Organization Name
Principal Investigator
Award
Title
California
Duarte
City of Hope/Beckman Research Institute Yu, Hua E
$293,751
Stat3 and anti-VEGF therapy
in cancer
La Jolla University of California San Diego Tukey,
Robert H
$412,751
Regulated Properties of the Human UGT1A1 Gene
University of California San Diego Lindquist,
Jeffrey N
$48,796
Role of Src in the endothelial response to VEGF
Los Angeles University of California Los Angeles Nelson,
Stanley F
$505,657
SNP studies in ADHD linked regions
University of Southern California Zhou, Xianghong Jasmine
$203,438
Integrative Analysis of Cross-Platform Microarray Data
San Francisco University of California San Francisco Miller, Walter L
$299,578
Pharmacogenomics of Human P450 Oxidoreductase
University of California San Francisco Scanlan,
Thomas S
$360,251
Ligand Pharmacology of Estrogen Receptors
Stanford Stanford University Sherlock,
Gavin J
$390,600
Continued Development of Stanford Microarray Database
Georgia
Atlanta
Emory University Morgan,
Edward T
$254,984
Regulation of CYP proteins by reactive nitrogen species
Massachusetts
Cambridge
Massachusetts Institute of Technology Plenge,
Robert M
$121,230
Mapping HIV/AIDS genes with haplotype-based strategies
Minnesota
Rochester
Mayo Clinic College of Medicine, Rochester Bram,
Richard J
$287,360
CAML in Normal and Oncogenic Functions of the EGFR
New York
Rochester
Enslein Research, Inc. Enslein, Kurt Nmi
$155,415
QSAR Models: Human CYP450 Drug Metabolism and Kinetics
New York Columbia University New York Morningside Firestein,
Stuart J
$336,614
Microarray Analysis of Olfactory Receptor Expression
Yeshiva University Terman,
Bruce I
$287,408
Nck and Crk in VEGF-Induced Endothelial Cells Migration
Ohio
Columbus
Ohio State University Cooke,
Glen E
$136,571
Pharmacogenetic Antiplatelet Strategies in CHD Patients
Tennessee
Nashville
Vanderbilt University Brown,
Nancy J
$306,157
Pharmacogenetics of ACE inhibitor-associated angioedema
Vanderbilt University Ni, Terri T
$152,334
Cross-experiment Microarray Data Normalization
Vanderbilt University Dikov,
Mikhail M
$272,048
The Role of VEGF in Hematopoiesis in Cancer
Virginia
Richmond
Virginia Commonwealth University Abraham,
Donald J
$300,275
Rational Design of Novel Estrogen Receptor Antagonists
Washington
Seattle
Fred Hutchinson Cancer Research Center Petersdorf,
Effie W
$326,363
Clinical Significance of MHC Haplotypes in HCT
*SOURCE: US National Institutes of Health

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The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.