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Nanogen s Molecular Biological Analysis and Diagnostics Including Waveguides and PerkinElmer s MultiPROBE II


The US Patent and Trademark Office this week issued Nanogen Patent Number 6,821,729 for a “Device for Molecular Biological Analysis and Diagnostics Including Waveguides,” the company said in a statement. The patent covers Nanogen’s positioning of a chip’s components to deliver light by “integrated waveguides,” which allow a “smaller and more compact” device design and “improves” fluorescent detection, the company said.

PerkinElmer this week announced the launch of its MultiPROBE II forensic workstation, which “reliably” performs automated DNA processing procedures, including isolation, QPCR setup, normalization and dilution, and typing PCR setup, the company said.

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The Scan

Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures

In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.

Family Genetic Risk Score Linked to Diagnostic Trajectory in Psychiatric Disorders

Researchers in JAMA Psychiatry find ties between high or low family genetic risk scores and diagnostic stability or change in four major psychiatric disorders over time.

Study Questions Existence of Fetal Microbiome

A study appearing in Nature this week suggests that the reported fetal microbiome might be the result of sample contamination.

Fruit Fly Study Explores Gut Microbiome Effects on Circadian Rhythm

With gut microbiome and gene expression experiments, researchers in PNAS see signs that the microbiome contributes to circadian rhythm synchronicity and stability in fruit flies.