Modeling Parkinson's

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Researchers at the Whitehead Institute at MIT have used a forward chemical genetics approach to identify natural-product-like molecules that could be useful in finding new drug targets for Parkinson's disease. In the study, a team from Susan Lindquist's lab used yeast cells to synthesize an enormous library of cyclic peptides, and then found two that were capable of saving the cells from alpha-synuclein, a toxic protein implicated in the development of Parkinson's disease.

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