Mayo Oncologists Use Single-Gene Test to Guide Three-Drug Chemotherapy | GenomeWeb

A simple single-gene test can guide chemotherapy dosing and help prevent toxicity common to a particular three-drug regimen, according to preliminary results presented last week at the American Society of Clinical Oncology in Orlando, Fla., by researchers from the Mayo Clinic.

The three drugs — irinotecan, oxaliplatin, and capecitabine — are considered the best chemotherapeutics for gastrointestinal cancer, Matthew Goetz, an assistant professor of oncology at the Mayo Clinic in Rochester and head researcher of the study, told Pharmacogenomics Reporter.

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