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Interleukin Genetics

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Interleukin Genetics has won a patent from the US Patent and Trademark Office for the discovery that “certain common” SNPs in the Interleukin-1 genes are linked to an increased risk for osteoporosis. In a recent study, the company showed that certain SNPs in the IL-1 genes “produce lifelong tendencies to have more inflammation or qualitative differences in inflammation mechanisms. Any one of different IL-1 SNPs leads to altered levels of inflammation and is associated with an increased risk of bone fractures,” the firm said.

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The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.