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Epicentre, BD Biosciences, PyroMark ID

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Epicentre has released its Fail-Safe Probes Real-Time PCR Optimization Kit this week, which allows "fast and easy optimization" of efficiency and specificity in one round of PCR experiments using target-specific probes, the company said in a statement. The kit contains the company's FailSafe Enzyme Blend and a set of 8 PCR 2X PreMixes that "represent a complete range of PCR conditions," Epicentre said. The kit is compatible with "all real-time PCR instrument platforms and types of fluorescently labeled probes," Epicentre added.


BD Biosciences launched its QTaq ROX-free DNA Polymerase Kit for quantitative PCR last week. The kit provides ROX dye separately, allowing users to adjust its concentration or omit it for optimal signal, the company said.


PyroMark ID is a new Biotage system for the identification and resistance typing of microorganisms launched last week. It is "designed to provide real-time sequencing for clinical microbiologists for high-throughput identification of clinically important bacteria, fungi and viruses," the company said in a statement. The system also interrogates SNPs linked to antibiotic resistance, the company added.

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The Scan

Researchers Develop Polygenic Risk Scores for Dozens of Disease-Related Exposures

With genetic data from two large population cohorts and summary statistics from prior genome-wide association studies, researchers came up with 27 exposure polygenic risk scores in the American Journal of Human Genetics.

US Survey Data Suggests Ancestry Testing Leads Way in Awareness, Use of Genetic Testing Awareness

Although roughly three-quarters of surveyed individuals in a Genetics in Medicine study reported awareness of genetic testing, use of such tests was lower and varied with income, ancestry, and disease history.

Coral Genome Leads to Alternative Amino Acid Pathway Found in Other Non-Model Animals

An alternative cysteine biosynthesis pathway unearthed in the Acropora loripes genome subsequently turned up in sequences from non-mammalian, -nematode, or -arthropod animals, researchers report in Science Advances.

Mosquitos Genetically Modified to Prevent Malaria Spread

A gene drive approach could be used to render mosquitos unable to spread malaria, researchers report in Science Advances.