Emory University to Establish Center for Systems Vaccinology | GenomeWeb

Emory University's Bali Pulendran and his colleagues demonstrated in late 2008 that a systems biology methodology could be used to predict the immunogenicity of the yellow fever vaccine in humans. By integrating high-throughput technologies, informatics, and computational modeling, Pulendran's team set the stage for systems vaccinology — an approach that allows investigators to track the "dynamic changes in the expression of mRNA, microRNAs, and proteins during an immune response to a vaccine," he says.

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