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Earl Collier, Craig Tuttle, Mike Summers, Illumina, Applied Biosystems, GenVault, CombiMatrix



DeCode Genetics this week said that it has named Earl "Duke" Collier to its board of directors, effective immediately. Collier is an executive vice president at Genzyme and previously served as president of Vitas Healthcare and as a partner at the Washington, DC-based law firm Hogan and Hartson. Prior to that position, he served as deputy administrator of the Health Care Finance Administration — now the Centers For Medicare and Medicaid Services — in the US Department of Health and Human Services. He earned a BA from Yale University and a JD from the University of Virginia.

Transgenomic said this week that its board of directors has elected Craig Tuttle as the company's president and chief executive officer, effective immediately. Tuttle will be based at the company's Omaha headquarters. He will succeed Mike Summers, who served as interim chief executive officer, and who will continue as the company's chief financial officer.

Tuttle previously served as president and COO of Duke Scientific, a specialty chemistry manufacturer, where he led its sale to Fisher Healthcare in 2005. Prior to that position, he was the president of Applied Biotech, the home pregnancy test manufacturer. Before that, he ran Seradyn, a specialty chemical and diagnostic test manufacturer.

Tuttle has also held management positions with Boehringer Mannheim, Bayer Healthcare, and Cetus.

Tuttle earned a BS in biochemistry from the University of California, Los Angeles, an MS in biochemistry from the University of Colorado, and an MBA from St. Mary's College.


New Releases

Illumina last week launched two Infinium genotyping products for whole-genome and focused-content SNP genotyping.

The HumanHap550+ product enables customers to add up to 120,000 custom SNP markers to supplement the standard content provided on the company's HumanHap550 BeadChip, yielding up to 670,000 markers for association studies, the company said.

For focused-content genotyping, the iSelect Infinium product allows customers to create a custom array of up to 60,000 SNP markers per sample with 12 samples per chip. The multi-sample offering will typically be used by researchers who have already performed whole-genome genotyping and/or have narrowed down SNPs of interest to a large but focused set of markers relevant to the particular disease they are studying, the company added.

The firm offers its custom Infinium genotyping products as either a product or a service, and also offers the use of software that enables in silico SNP design and screening before probe synthesis.

Applied Biosystems last week said that it has added "more than a million" new assays to its collection of pre-designed, TaqMan SNP Genotyping Assays.

The new assays provide access to the recently completed International HapMap data set and include more than 11,000 new assays for putative functional coding SNPs.

The company also said that it has updated its free SNPbrowser software tool to include the entire HapMap data set and the newly available genotyping assays. The SNPbrowser software allows scientists to visualize SNPs of interest in their genomic context, along with linkage disequilibrium maps and putative haplotype blocks derived from the analysis of more than six million SNPs and 650 million genotypes for four ethnic populations: African-American, Caucasian, Chinese and Japanese.

GenVault last week launched its Bank in a Box promotion aimed at customers interested in replacing freezers with a room-temperature, dry DNA-storage system. The promotion includes the company's GenPlate multi-well DNA storage plate embedded with aliquots of media for archiving DNA from a variety of biosample types. It also includes GenCode, a permanent sample identification system consisting of an oligonucleotide-based tag that co-migrates with the sample through downstream analysis.

The introductory system comes with a pack of 20 GenPlates in any configuration, a limited edition of GenConnect sample management software and one Desktop Archive storage module with 38,400-aliquot capacity.

CombiMatrix last week introduced its QuadroCAS CustomArray Synthesizer. Co-developed with Japanese life sciences company Furuno Electric, CombiMatrix said that the QuadroCAS system can fabricate up to four in situ arrays simultaneously in 24 hours or less.

The synthesizer also incorporates all reagents and hardware into a stand-alone instrument, including Furuno's instrument-control and signal-processing electronics.

According to CombiMatrix, the QuadroCAS offers "smaller run batch sizes, low- to medium-density array formats, on-board reagents, and a smaller footprint" compared to the firm's CustomArray Synthesizer, which is geared for customers needing "higher production throughput, low, medium and high density array formats."

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