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DxS, Exosome to Collaborate on Cancer Dx Tests

NEW YORK (GenomeWeb News) – DxS and Exosome Diagnostics said today that they will collaborate on developing blood-based companion diagnostics for cancer gene mutations, such as KRAS, BRAF, and EGFR.

Under the collaboration, the firms will team DxS' Scorpions real-time PCR Mutation Test Kits with Exosome's xOS technology for harvesting nucleic acids from blood exosomes. The firms hope to develop test kits that will measure gene mutations in blood and predict patient response to targeted therapies.

"Combining the ability to pull high-quality mutations from a simple blood draw with the unparalleled sensitivity and specificity of our Scorpion assays will provide our pharmaceutical and research customers with an ideal solution in personalized medicine," DxS CEO Stephen Little said in a statement.

Financial and further terms of the alliance were not disclosed.

The Scan

Purnell Choppin Dies

Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.

Effectiveness May Decline, Data From Israel Suggests

The New York Times reports that new Israeli data suggests a decline in Pfizer-BioNTech SARS-CoV-2 vaccine effectiveness against Delta variant infection, though protection against severe disease remains high.

To See Future Risk

Slate looks into the use of polygenic risk scores in embryo screening.

PLOS Papers on Methicillin-Resistant Staphylococcus, Bone Marrow Smear Sequencing, More

In PLOS this week: genomic analysis of methicillin-resistant Staphylococcus pseudintermedius, archived bone marrow sequencing, and more.