Skip to main content
Premium Trial:

Request an Annual Quote

Drug Abuse Institute Seeks PGx Proposals


The National Institute on Drug Abuse's medications development program is soliciting proposals on the pharmacogenetics of drug addiction.

"The genetics component of the clinical trials will focus on the identification of pharmacogenetic factors that predict patient response to medications and/or between-subject variations in pharmacokinetics, as well as the identification of biomarkers for addiction," NIDA said in a presolicitation issued last week.

Specifically, NIDA is interested in funding investigators that wish to "conduct the related DNA and RNA analyses on blood samples collected from … studies, to interpret the data, and to write high-quality reports and publications that summarize important findings."

NIDA is interested in seeing proposals for genotyping using Affymetrix GeneChip Mapping 500K array sets or equivalent platforms or proposals for expression analyses using Human Genome U-133 Plus 2.0 arrays or similar technology.

Winning proposals will be given a five-year contract in which NIDA will reimburse the cost of the PGx analysis.

NIDA said that the request for proposals will be available electronically around Jan. 28. Investigators interested in submitting a proposal should do so by March 14.

"NIDA will consider proposals submitted by any responsible offeror," the institute said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.