Does Mutation That Protects Against Alzheimer s Increase Parkinson s Risk? | GenomeWeb

A recent meta-analysis of 22 studies found that a variant in the apoliprotein E gene that protects against Alzheimer’s disease increases by 20 percent the risk of developing Parkinson’s disease.

The study of the variant, APOE-2, “basically shows that neurodegenerative diseases may differ in significant risk factors, contrary to prevailing views,” Xuemei Huang, assistant professor of neurology at the University of North Carolina, Chapel Hill, School of Medicine, said in a statement.

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