NEW YORK (GenomeWeb News) – Clinical Data said today that the biomarker it had previously associated with response to its depression drug candidate vilazodone did not replicate its earlier success in the firm's most recent phase III study of the drug.

The Newton, Mass.-based drug developer and pharmacogenomic test maker reported positive top-line results from the second of two phase III studies of vilazodone. Clinical Data said that the drug achieved statistically significant results on the primary and secondary endpoints related to major depressive disorder.