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Clarification: Mar 3, 2005


The most recent issue of Pharmacogenomics Reporter omitted the journals in which secondary Tarceva- and Iressa-resistance research papers were published. The research group from Beth Israel Deaconess Medical Center published in the Feb. 24 issue of The New England Journal of Medicine, while the group from the Memorial Sloan-Kettering Cancer Center published in the Feb. 22 issue of PLoS Medicine.

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The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.