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In Brief This Week: CombiMatrix; SQI Diagnostics, Gamma-Dynacare; NuGen; Evotec; WaferGen Biosystems

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – CombiMatrix said this week that its subsidiary, CombiMatrix Molecular Diagnostics, has received approval from Medicare to begin billing for its array-based diagnostic tests. The subsidiary offers array-based cancer tests through its Irvine, Calif.-based CLIA-certified lab.

Gamma-Dynacare Medical Laboratories will begin offering SQI Diagnostics' multiplex IgXplex Rheumatoid Arthritis test through its lab services in Canada. The firms are also in discussions for Gamma-Dynacare to beta test SQI's celiac panel.

NuGen said this week that it has received cGMP certification from the State of California for the manufacture and shipping of its RNA and DNA sample preparation products. The firm noted that it had already received ISO 13485 certification.

Evotec said that it will receive a €2.5 million ($3.1 million) milestone payment from Boehringer Ingelheim for selection of a candidate compound for pre-development studies in an oncology program. The firms have been collaborating since 2004 in a variety of disease areas.

WaferGen Biosystems today said that researchers at Kyoto University will use the firm's SmartChip Real-Time PCR System to identify and compare biomarkers that may be associated with tissue regeneration. It noted that Kyoto University is one of the firm's early-access customers for the SmartChip system.

Jackson Laboratory associate research scientist Julie Wells has received a $90,000 grant from the Maine Cancer Foundation for a research titled "MicroRNA expression during lung tumor progression." The grant is part of three awarded by the foundation to Jackson Lab researchers to conduct research into cancer.

The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.