Skip to main content
Premium Trial:

Request an Annual Quote

AdvanDx Gets FDA OK for Dual Pathogens Test

NEW YORK (GenomeWeb News) – AdvanDx has received US Food and Drug Administration clearance for its E. coli/P. aeruginosa PNA FISH assay to identify Escherichia coli and/or
Pseudomonas aeruginosa directly from positive blood cultures.

Woburn, Mass.-based AdvanDx said that the dual-pathogen assay is the first ever test for identifying E. coli and P. aeruginosa directly from positive blood cultures. The test, which is based on AdvanDx's peptide nucleic acid probe technology, can provide rapid species identification in hours rather than days and enable therapy guiding results for 95 percent to 99 percent of patients with positive blood cultures.

According to AdvanDx, studies have shown that a 24-hour head start on appropriate therapy for Gram-negative bloodstream infections may improve clinical outcomes, reduce antibiotic resistance rates and reduce the incidences of adverse events.

The Scan

Long COVID-19 Susceptibility Clues Contained in Blood Plasma Proteome

A longitudinal study in eBioMedicine found weeks-long blood plasma proteome shifts after SARS-CoV-2 infection, along with proteomic signatures that appeared to coincide with long Covid risk.

Tibetan Study Finds Adaptive Variant Influencing Skin Pigmentation

With a combination of phenotyping and genetic data, researchers document at PNAS a Tibetan-enriched enhancer variant influencing melanin synthesis and ultraviolet light response.

Domestication Linked to Nervous System Genes in Inbred Mouse Strains

Researchers highlighted more than 300 positively selected genes in domesticated mice, including genes linked to nervous system function or behavior in Genome Biology.

ALS Genetic Testing May Be Informative Across Age Ranges, Study Finds

Researchers in the journal Brain identified clinically actionable variants in a significant subset of older ALS patients, prompting them to point to the potential benefits of broader test use.