tamoxifen Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response Premium Researchers have developed a computational method that considers uncommon CYP2D6 variants to assess patient-specific metabolism of tamoxifen and other drugs. Biotheranostics' Breast Cancer Index Included in Latest NCCN Guidelines The expert body now recognizes the test's ability to predict whether early-stage breast cancer patients will benefit from extended, adjuvant endocrine therapy. OncotypeDX Score May Give Valuable Info on Breast Cancer Locoregional Recurrence Such prognostic information could aid clinicians in making decisions about radiotherapy for postmenopausal women with breast cancer. Tumor Heterozygosity Loss May Explain Failure of Studies to Link CYP2D6, Tamoxifen Benefit Premium Data shows CYP2D6 testing in breast tumor tissue can be inaccurate due to loss of heterozygosity, and may have obscured the connection between genotype and tamoxifen response in previous trials. Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.