gilteritinib Japanese Regulators Approve Invivoscribe Assay as CDx for Daiichi Sankyo AML Drug The LeukoStrat CDx FLT3 Mutation Assay can now be used in Japan as the CDx for quizartinib for the treatment of FLT3-ITD positive relapsed or refractory AML. Single-Cell Sequencing Proves Useful for Tracking Drug-Resistant AML Mutation Progression Premium Researchers used Mission Bio's Tapestri assay to identify and monitor the evolution of cancer mutations in acute myeloid leukemia in response to targeted treatment. FLT3 Inhibitor Treatment Improves Survival in Relapsed, Refractory AML Patients With Mutations Results from the phase 3 ADMIRAL trial were announced during the American Association for Cancer Research annual meeting. First Veterans Affairs MDx Lab Launches NGS-Based Cancer Panel; Others to Follow Premium The VA decided to bring this testing in house to streamline and standardize the process for doctors and gauge markers that are relevant to the veteran population. Invivoscribe CDx Assay Gets Expanded FDA Approval Alongside Astellas AML Drug The LeukoStrat CDx FLT3 Mutation Assay is a PCR-based test for internal tandem duplications and tyrosine kinase domain mutations D835 and I836 in the FLT3 gene. Nov 27, 2018 Invivoscribe Submits FLT3 Mutation CDx Assay to FDA Nov 19, 2018 Invivoscribe Submits FLT3 Mutation Assay CDx to Japanese Regulators Sep 27, 2018 Invivoscribe Receives Regulatory Approval for FLT3 Mutation Assay in Japan Breaking News CDC Awards $22M to Combat Antimicrobial Resistance, Infectious Diseases Pan-Cancer Analysis Reveals Unique Features in Tumors From Younger People Breast Cancer Therapy Response Predicted by Multiomic Machine Learning Model Cytena Inks China Distribution Deal for Single-Cell Isolators Freenome Raises $300M in Series D Financing More Than Dozen Genetic Loci Linked to Amyotrophic Lateral Sclerosis Risk The Scan Less Than Half An effort to reproduce key findings from high-profile preclinical cancer studies finds less than half could be replicated, according to the Scientist. Still Some SARS-CoV-2 Sequencing Holes The Wall Street Journal reports that viral genomic surveillance has improved in the US, though says there are still gaps. Avoiding Passing Them On People with known disease-linked genetic variants are turning to in vitro fertilization so as to not pass those variants to their children, the Washington Post says. PNAS Papers on Long Cell-Free DNA in Maternal Plasma, Genetic Propensity for Voting In PNAS this week: long, cell-free DNA of maternal and fetal origins identified in maternal plasma, and more.