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Sep 10, 2020

FDA Joins PGx Collaborative Community but Effect on Field is Unclear

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The community is poised to be the primary channel for stakeholders to communicate PGx concerns with FDA, but it is unclear if all stakeholders will participate.

Aug 25, 2020

Trial Shows Some Benefit of Genetically Guided Antiplatelet Therapy After Balloon Angioplasty

The TAILOR-PCI trial did not meet its primary endpoint but did find that genetic testing led to a reduction in adverse events, though not as much as expected.

Aug 18, 2020

23andMe Garners FDA Clearance for CYP2C19 PGx Test Report

The firm can now tell customers if their genotypes may impact their response to clopidogrel and citalopram without the need for confirmatory testing.

Jan 28, 2020

Spartan Bioscience Pushing to Commercialize Personalized Heart Test

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The Ottawa-based molecular diagnostics maker also plans to enter applied markets in the near term, and ultimately point-of-care infectious disease testing.

Jul 08, 2015

New Analysis Examines Financial Impact of Genotyping Patients to Guide Anti-Platelet Therapy

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The latest analysis of CYP2C19 genotyping to guide antiplatelet therapy tries to address cost questions from the vantage of a payor or large healthcare system.

Nov 05, 2014

After Health Canada Approval, Spartan Plans to Launch Point-of-Care CYP2C19 Dx via Pharmacy Pilots

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Originally published Oct. 31.
NEW YORK (GenomeWeb) – Spartan Bioscience is gearing up to commercialize its CYP2C19 test in Canada in the point-of-care setting, a previously untapped market for the company.

Apr 16, 2014

Lawsuit in Hawaii against Plavix Sponsors Alleges Burden is on Pharma to Market PGx Information

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Can drugmakers be held liable for failing to aggressively warn consumers that patients with certain genetic markers will not respond or will have limited response to their drugs beyond just mentioning this information in drug labeling?

Nov 20, 2013

In Prescribing Study, Few Doctors Altered Treatment for Poor Plavix Metabolizers Based on Genotype

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A study led by researchers from Brigham and Women's Hospital on the effect of CYP2C19 testing on physicians' prescribing patterns has found that when doctors received patient test results for genetic markers associated with clopidogrel response through a pharmacy-benefit manager-

Oct 23, 2013

Transgenomic Enlists PDI to Market Cardiac PGx Test; PDI Entering MDx Space

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This article has been updated to note that PDI is moving away from the contract sales business with drug companies. Originally published Oct. 22.

Sep 12, 2013

Mount Sinai Group Publishes Allele-Specific PCR Assay for Novel CYP2C19 Variants

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Having published research last year identifying a novel haplotype that may alter the interpretation of CYP2C19 genotyping, clinical researchers from the Icahn School of Medicine at Mount Sinai in New York have now published a paper describing an allele-specific PCR assay to detec

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The Scan

And Maybe Not

President Donald Trump might not approve the stricter standards the US Food and Drug Administration is developing for authorizing a SARS-CoV-2 vaccine, according to Politico.

Now Onto a Hungry Caterpillar

Wired reports that Oxitec has now developed a genetically modified fall armyworm.

This Variant Here

A large genetic study finds SARS-CoV-2 viruses with a certain variant are spreading more than others, according to the Washington Post.

Nature Papers Present Tool for Topological Analysis of Chromosomes, Map of Genome-Lipid Associations

In Nature this week: sister-chromatid-sensitive chromosome conformation capture approach, and more.

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