ceritinib Moffitt Team Uses Proteomic Profiling to ID New Ceritinib Targets in Lung Cancer Premium The researchers combined different proteomic methods to explore the activity of the ALK inhibitor ceritinib and identify potential combination therapies. Roche ALK Test Gains FDA Approval as CDx for Zykadia The IHC test was used in clinical studies that led to Zykadia's approval last week as a first-line option for metastatic NSCLC patients with ALK rearrangements. Novartis' Zykadia Approved for Frontline Treatment of Metastatic, ALK-Positive NSCLC The expanded indication makes it a first-line option for metastatic non-small cell lung cancer patients with ALK rearrangements. EU's CHMP Grants Conditional Marketing Authorization to Novartis' Personalized NSCLC Rx Zykadia Premium Zykadia received conditional marketing authorization as a treatment for advanced NSCLC patients who've previously received the ALK inhibitor Xalkori, and so are known to be ALK positive. Breaking News Ancient DNA Analysis Highlights Three Ancestral Populations in Japan FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.