afatinib Roche EGFR Mutation Test Approved by FDA as Companion Diagnostic for NSCLC Roche's real-time PCR test detects defined mutations of the epidermal growth factor receptor gene in DNA from non-small cell lung cancer patients. Cervical Cancer Exomes Point to Potentially Targetable HER, PIK3CA Pathway Changes Exome sequences from dozens of cervical cancer tumor or primary cell line samples revealed recurrent alterations affecting ERBB2/HER2 and PIK3CA pathways. TAPUR Study Investigators Report First Positive Findings, Pursuing Tissue-Agnostic Cohorts Premium Keytruda and Ibrance demonstrate activity in molecularly defined populations, while a new cohort will explore Gilotrif in tumors with NRG1 fusions. Breast, Lung Cancer Genetics Highlight Mutations Linked to Drug Response, Prognosis New tumor profiling papers stemming from prior clinical trials led to informative mutations in early-stage, ER+/HER2- breast cancer and lung squamous cell carcinoma. Breaking News CDC Awards $22M to Combat Antimicrobial Resistance, Infectious Diseases Pan-Cancer Analysis Reveals Unique Features in Tumors From Younger People Breast Cancer Therapy Response Predicted by Multiomic Machine Learning Model Cytena Inks China Distribution Deal for Single-Cell Isolators Freenome Raises $300M in Series D Financing More Than Dozen Genetic Loci Linked to Amyotrophic Lateral Sclerosis Risk The Scan Less Than Half An effort to reproduce key findings from high-profile preclinical cancer studies finds less than half could be replicated, according to the Scientist. Still Some SARS-CoV-2 Sequencing Holes The Wall Street Journal reports that viral genomic surveillance has improved in the US, though says there are still gaps. Avoiding Passing Them On People with known disease-linked genetic variants are turning to in vitro fertilization so as to not pass those variants to their children, the Washington Post says. PNAS Papers on Long Cell-Free DNA in Maternal Plasma, Genetic Propensity for Voting In PNAS this week: long, cell-free DNA of maternal and fetal origins identified in maternal plasma, and more.