NEW YORK (GenomeWeb) – Pursuing drug targets that have supporting genetic evidence could double the clinical development success rate, according to researchers led by GlaxoSmithKline's Philippe Sanseau.

More than half of clinical trials fail because the drugs are not effective, and drawing on genes that have been linked to disease could help inform the drug target selection process and make it more successful.

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Jun
05
Sponsored by
Linguamatics

This webinar will discuss how Sanofi used literature mining to annotate the association of human leukocyte antigen (HLA) alleles with diseases and drug hypersensitivity as part of a multiple sclerosis (MS) biomarker discovery project.

Jun
19
Sponsored by
Advanced Cell Diagnostics

This webinar will provide evidence for the use of RNA in situ hybridization (RNA ISH) as a replacement for immunohistochemistry (IHC) in cancer research and diagnostic applications.

Jun
26
Sponsored by
Lexogen

This webinar outlines a study that sought to characterize the landscape of alternative polyadenylation (APA) in the lung cancer transcriptome in order to gain insight into the role of APA in cancer progression.