Drug Discovery & Development

News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.

Roche, Genialis Partner to Develop Streamlined NGS Workflow for Drug Discovery

The new RNA sequencing analysis workflow integrates Roche's RNA-seq library kits with Genialis' automated data processing pipeline for gene expression analyses.

Team Taps Large Population PheWAS For Clues to Drug Targets, Side Effects

The phenome-wide association study focused on SNPs near potential drug target sites with ties to one or more phenotypes that might impact target suitability.

FDA Guidances Elucidate Agency's Regulatory Thinking on Precision Oncology Drug Development

The agency issued draft guidance on minimal residual disease as a biomarker and finalized another guidance on developing drugs with pan-cancer indications.

Researchers Explore Variety of Response Markers in Melanoma Study of Combo Checkpoint Inhibitors

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Using samples from different points in patients' treatment, researchers employed a variety of tools, including NanoString's GeoMx DSP, to explore potential response markers.

Epic Sciences Continues Research on Multiple Fronts; Remains Quiet on Dx Development Pipeline

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New data has shown that the firm's platform could help stratify patients for treatment with antibody-drug conjugates by finding those whose CTCs express enough of the target.

Oct 03, 2018

Centogene, Denali Therapeutics Partner to Recruit Parkinson's Patients for Drug Program

Oct 01, 2018

Attagene Profiles Chemical Effects, Toxicity With Multiplex Reporter System Assays

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Sep 26, 2018

Konica Minolta Launches Precision Medicine Business

Sep 25, 2018

Signatope Partners With CPATH to Apply Immuno-MS Approach to Drug Toxicity Testing

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Sep 20, 2018

European Cancer Charities Award $39.4M in Research Grants

Sep 20, 2018

Celldom to Tackle Single-Cell Analysis Sector With Integrated Genotyping, Phenotyping Platform

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Sep 19, 2018

Drugs Targeting Lipolysis Could Confer Additional Cardiovascular Benefit, Genetic Analysis Finds

Sep 14, 2018

Repositive to Launch Personalized Cancer Model Matching Service

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Sep 12, 2018

CellDom Wins $1.5M NIH Grant To Develop Single-Cell Analysis Platform

Sep 11, 2018

UMich Researcher Wins $6.5M NCI Outstanding Investigator Award

Sep 06, 2018

Evotec, Celgene Partner on Targeted Protein Degradation for Drug Discovery

Aug 31, 2018

Opium Poppy Genome Provides Look at Painkiller Compound Evolution

Aug 30, 2018

Genomics Plc Raises £25M, Collaborates With Vertex on Precision Medicine

Aug 27, 2018

Centogene, Evotec Forge Drug-Discovery Alliance

Aug 23, 2018

U of Miami Medicine Wins $3M NIH Grant for Hearing Loss Genetics Research

Aug 21, 2018

Gene Editing Firm Recombinetics Closes $34M Series A Round

Jul 31, 2018

New Mouse Models for Late-Onset Alzheimer's Disease May Advance Biomarker, Drug Discovery

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Jul 26, 2018

GSK, 23andMe Gamble on Personalized Drug Discovery With Exclusive Deal

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Jul 25, 2018

23andMe, GSK Ink Exclusive Drug Target Discovery Pact

Jul 17, 2018

Strata Oncology to Aid Puma Biotech in Recruiting for Neratinib HER2 Basket Study

The Scan

In on the Action

NPR reports that with medical data being big business, some companies want to get patients involved.

What's in Store?

The Asbury Park Press reports on the startup Genomic Prediction's test to determine an embryo's risk of disease.

This Week in PNAS

In PNAS this week: optical mapping allows glimpse of structural variants, disease-linked GATA2 mutations boosts its protein activity, and more.

Warren Releases Genetic Ancestry Results

Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Featured White Papers

NGS is Accelerating Therapeutic Antibody Discovery - What Lies Beyond?

iPSC & CRISPR/Cas9 Technologies Enable Precise & Controlled Physiologically Relevant Disease Modeling for Basic & Applied Research

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Discovering Neuronal Cell Types

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Featured Webinar

Glass or Polymer? A Comparison for Use in In Vitro Diagnostic Biochips

This webinar will discuss how understanding the relative performance characteristics of glass and polymer substrates for in vitro diagnostic applications such as microarrays and microfluidics can help to optimize diagnostic performance.

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