Drug Discovery & Development

News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.

Centogene Inks Drug Discovery, Development Deal With Chiesi

The companies will work together to identify the genetic mutations that cause the rare genetic lysosomal storage disorder alpha mannosidosis.

GeneCentric, UNC Collaborate on Bladder Cancer Immunotherapy Response Study

The partners will evaluate patients' responses to immunotherapeutic drugs, including PD-1 and PDL-1 inhibitors, based on bladder cancer subtypes.

Cofactor Genomics Inks Pilot Study Deal for Immune Profiling Kit Evaluation

Cofactor's kit will be used to characterize the immune responses generated in reaction to treatment with an investigational personalized cancer vaccine.

TwoXAR Partners With Adynxx for Endometriosis Drug Discovery

TwoXAR's proprietary artificial intelligence technology uses a variety of biomedical data including genomic, proteomic, and clinical data for drug discovery.

NCI-MATCH Patients With AKT1-Mutated Cancers Respond Well to AstraZeneca Drug

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In this arm of the trial, 23 percent of patients treated with AKT1 E17K mutations saw their tumors shrink, a better result than those seen in three other trial arms.

Oct 30, 2018

Precision Oncology Highlights From ESMO 2018

Oct 26, 2018

Schizophrenia Drug Screening Improved Through Use of Patient-Derived Cells

Oct 16, 2018

Roche, Genialis Partner to Develop Streamlined NGS Workflow for Drug Discovery

Oct 16, 2018

Team Taps Large Population PheWAS For Clues to Drug Targets, Side Effects

Oct 15, 2018

FDA Guidances Elucidate Agency's Regulatory Thinking on Precision Oncology Drug Development

Oct 11, 2018

Researchers Explore Variety of Response Markers in Melanoma Study of Combo Checkpoint Inhibitors

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Oct 03, 2018

Epic Sciences Continues Research on Multiple Fronts; Remains Quiet on Dx Development Pipeline

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Oct 03, 2018

Centogene, Denali Therapeutics Partner to Recruit Parkinson's Patients for Drug Program

Oct 01, 2018

Attagene Profiles Chemical Effects, Toxicity With Multiplex Reporter System Assays

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Sep 26, 2018

Konica Minolta Launches Precision Medicine Business

Sep 25, 2018

Signatope Partners With CPATH to Apply Immuno-MS Approach to Drug Toxicity Testing

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Sep 20, 2018

European Cancer Charities Award $39.4M in Research Grants

Sep 20, 2018

Celldom to Tackle Single-Cell Analysis Sector With Integrated Genotyping, Phenotyping Platform

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Sep 19, 2018

Drugs Targeting Lipolysis Could Confer Additional Cardiovascular Benefit, Genetic Analysis Finds

Sep 14, 2018

Repositive to Launch Personalized Cancer Model Matching Service

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Sep 12, 2018

CellDom Wins $1.5M NIH Grant To Develop Single-Cell Analysis Platform

Sep 11, 2018

UMich Researcher Wins $6.5M NCI Outstanding Investigator Award

Sep 06, 2018

Evotec, Celgene Partner on Targeted Protein Degradation for Drug Discovery

Aug 31, 2018

Opium Poppy Genome Provides Look at Painkiller Compound Evolution

Aug 30, 2018

Genomics Plc Raises £25M, Collaborates With Vertex on Precision Medicine

Breaking News

The Scan

Blame the Follicles

A genome-wide association study highlights a potential role for hair follicles in acne risk, according to New Scientist.

Missed a Few

Newsday reports that breast cancer genetic testing guidelines for are out of date and may miss individuals.

This Week in Cell

In Cell this week: gene editing-based strategy to screen for immune system regulators, ancient plague patterns, and more.

Yep, Couple of Concerns There

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

Featured White Papers

NGS is Accelerating Therapeutic Antibody Discovery - What Lies Beyond?

Powerful Bioinformatic Support for Specialized Therapeutic Antibody Discovery

Discovering Neuronal Cell Types

How to Use CrownBio's Integrated Oncology Portfolio for Target Identification and Mechanism of Action Elucidation

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Featured Webinar

Leveraging Single-Cell Genomics to Identify Drivers of Enhanced Immunity

This webinar highlights the use of single-cell genomics to identify distinct cell types and states associated with enhanced immunity.