Drug Discovery & Development

News on drug screening, clinical trials, companion diagnostics, immunotherapy, & personalized therapies in genetics, genomics, and molecular diagnostics.

AbCellera, Novartis Partner on Antibody Drug Discovery

The firms will use AbCellera's antibody discovery platform, which combines a variety of technologies including next-generation sequencing and bioinformatics.

Lonza to Sell AllCells Hematopoietic Primary Cell Products

The deal expands Lonza's portfolio of hematopoietic cell lines, including mobilized peripheral blood progenitor cells, for research applications.

Twist Bioscience Grows SynBio Business, Invests in NGS While Battling Agilent Lawsuit

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Twist continues to invest in NGS while growing its core synthetic biology business, and has filed a countercomplaint in its ongoing litigation with Agilent.

Arivale Partners to Mine Growing Customer Data for Rx, Dx Insights

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The company is working with partners to identify new biomarkers and treatments as well as to collect utility evidence for its current coaching model.

Antimicrobial Candidate Found in Insect Microbiome Analysis

With metagenomics, genomics, and other analyses, researchers saw a potential antifungal compound called cyphomycin produced by Streptomyces in an ant in Brazil.

Jan 29, 2019

Sphere Fluidics Closes $2M Financing Round

Jan 18, 2019

Sphere Fluidics, Peak Analysis Partner for Single-Cell Analysis

Jan 04, 2019

Adaptive Biotechnologies, Genentech Form Personalized Cancer Therapy Partnership

Dec 20, 2018

Twist Bioscience to Open Manufacturing Facility in China; Sees Strong Demand for NGS Products

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Dec 20, 2018

Bayer, HitGen Partner on Small Molecule Discovery for Crop Science

Dec 19, 2018

Celmatix Forms Therapeutics Discovery Division

Dec 18, 2018

Bristol-Myers Squibb, Boston Medical Center Partner to Study Immuno-Oncology Response, Resistance

Dec 18, 2018

OncoImmunity Wins €2.2M in European Funding for Neoantigen Prediction Tech

Dec 17, 2018

Bristol-Myers Squibb, H3 Biomedicine Form Cancer Immunotherapy Alliance

Dec 11, 2018

Centogene Inks Drug Discovery, Development Deal With Chiesi

Dec 10, 2018

GeneCentric, UNC Collaborate on Bladder Cancer Immunotherapy Response Study

Dec 04, 2018

Cofactor Genomics Inks Pilot Study Deal for Immune Profiling Kit Evaluation

Nov 16, 2018

TwoXAR Partners With Adynxx for Endometriosis Drug Discovery

Nov 12, 2018

NCI-MATCH Patients With AKT1-Mutated Cancers Respond Well to AstraZeneca Drug

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Oct 30, 2018

Precision Oncology Highlights From ESMO 2018

Oct 26, 2018

Schizophrenia Drug Screening Improved Through Use of Patient-Derived Cells

Oct 16, 2018

Roche, Genialis Partner to Develop Streamlined NGS Workflow for Drug Discovery

Oct 16, 2018

Team Taps Large Population PheWAS For Clues to Drug Targets, Side Effects

Oct 15, 2018

FDA Guidances Elucidate Agency's Regulatory Thinking on Precision Oncology Drug Development

Oct 11, 2018

Researchers Explore Variety of Response Markers in Melanoma Study of Combo Checkpoint Inhibitors

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The Scan

For Fewer Mosquitos

NPR reports that researchers in Italy are testing a gene drive aimed at controlling mosquito populations.

Lasting Mark

Researchers may experience the effects of the government shutdown for a while, the Los Angeles Times reports.

To Know What's Wrong

A new study finds that the majority of patients at a Tijuana clinic received a diagnosis after first-line genome sequencing, the San Diego Union-Tribune reports.

This Week in Genome Biology

In Genome Biology this week: post-transcriptional modification-based stratification of glioblastoma, single-cell analysis of gene expression and methylation in human iPSCs, and more.

Featured White Papers

NGS is Accelerating Therapeutic Antibody Discovery - What Lies Beyond?

Powerful Bioinformatic Support for Specialized Therapeutic Antibody Discovery

How to Use CrownBio's Integrated Oncology Portfolio for Target Identification and Mechanism of Action Elucidation

Immuno-Oncology: 3 Strategies for Applying Humanized Models

Feb

26

Featured Webinar

A Cellular and Molecular Phenotyping Pipeline for Target Characterization in FFPE Biobank Samples

This webinar will demonstrate how a research team at the Firestone Institute for Respiratory Health at McMaster University developed a cellular and molecular phenotyping pipeline using archived samples of lung tissue derived from patients diagnosed with fibrotic interstitial lung disease.

Mar

14

Featured Webinar

A Multiomics Approach to Defining the Nature of Early Malignant Transformations of the Immune System

In this webinar, Dr. Wendy Béguelin of Weill Cornell Medicine will discuss how she used the BD Rhapsody single-cell RNA-seq platform and YFP floxed reporter mouse models to study how lymphoma-associated mutations disrupt the immune system by affecting GC B-cell states, explaining the biology of initiation of low-grade follicular lymphoma.

Mar

27

Featured Webinar

How One NGS Core Lab Reduced Sequencing Costs with a Novel Library Normalization Kit

Sequencing workflows require library quantification and normalization to ensure data quality and reduce cost.

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