vascular disease KRAS Mutations Revealed in Rare Vascular Brain Condition Researchers identified somatic KRAS mutations in affected tissue from more than 60 percent of people with sporadic arteriovenous malformations of the brain. HDL Cholesterol Boost Alone Does Not Reduce Cardiovascular Disease Risk, Genetic Study Suggests Tapping into genetic variation in the CETP gene, investigators explored blood lipid and disease effects of high-density cholesterol changes. Panel Sequencing Leads to Pathogenic Mutations in Autoinflammatory Cases With new gene sequencing panels, investigators made firm or possible diagnoses in almost one-third of undiagnosed autoinflammation and vasculitis cases. Proteomic Analysis Uncovers Role For PARP9, PARP14 in Macrophage Activation A team of researchers from Brigham and Women's Hospital and Harvard Medical School found that the two proteins appear to have opposing effects. Vermillion Presents Protein Biomarker Study Supporting OVA2 Ovarian Cancer Test Premium According to the company, the study, which was presented at the 42nd Annual Meeting on Women's Cancer of the Society of Gynecological Oncologists, examined more than 20 candidate biomarkers, identifying three potentially useful analytes. Feb 3, 2011 Genomics Aids NIH Undiagnosed Disease Program Mar 5, 2009 NHLBI Set to Start Third Major Proteomics Program Premium Feb 26, 2009 IP Update: Feb 26, 2009 Premium Breaking News CDC Awards $22M to Combat Antimicrobial Resistance, Infectious Diseases Pan-Cancer Analysis Reveals Unique Features in Tumors From Younger People Breast Cancer Therapy Response Predicted by Multiomic Machine Learning Model Cytena Inks China Distribution Deal for Single-Cell Isolators Freenome Raises $300M in Series D Financing More Than Dozen Genetic Loci Linked to Amyotrophic Lateral Sclerosis Risk The Scan Less Than Half An effort to reproduce key findings from high-profile preclinical cancer studies finds less than half could be replicated, according to the Scientist. Still Some SARS-CoV-2 Sequencing Holes The Wall Street Journal reports that viral genomic surveillance has improved in the US, though says there are still gaps. Avoiding Passing Them On People with known disease-linked genetic variants are turning to in vitro fertilization so as to not pass those variants to their children, the Washington Post says. PNAS Papers on Long Cell-Free DNA in Maternal Plasma, Genetic Propensity for Voting In PNAS this week: long, cell-free DNA of maternal and fetal origins identified in maternal plasma, and more.