vascular disease
Candidate Genes for Condition Limiting Blood Flow to Extremities Identified by GWAS
Researchers tracked down three risk loci and two candidate risk genes for Raynaud's phenomenon with a genome-wide association study using UK Biobank data.
Varicose Vein GWAS Points to Vascular Risk Loci, Potential Treatment Targets
Starting with a multi-ancestry genome-wide association study, researchers unearthed varicose vein-related variants, along with related traits and treatment targets.
Brain Vascular Malformation Insights Gleaned From Single-Cell Atlas
With single-cell RNA sequencing, researchers characterized expression and cell type shifts in brain vascular samples from individuals with or without brain arteriovenous malformations.
KRAS Mutations Revealed in Rare Vascular Brain Condition
Researchers identified somatic KRAS mutations in affected tissue from more than 60 percent of people with sporadic arteriovenous malformations of the brain.
HDL Cholesterol Boost Alone Does Not Reduce Cardiovascular Disease Risk, Genetic Study Suggests
Tapping into genetic variation in the CETP gene, investigators explored blood lipid and disease effects of high-density cholesterol changes.