uterine cancer
Uterine Leiomyosarcoma Sequences Point to Potentially Targetable Somatic Mutations
Using genome, exome, or transcriptome sequences from dozens of uterine leiomyosarcoma samples, researchers found alterations that may respond to existing targetable treatments.
The team analyzed multigene panel test data from Ambry Genetics for 165,000 individuals, focusing on hereditary cancer risk related to 32 genes in six cancer types.
Pan-Cancer Study Uncovers TP53 Mutation Consequences, Related Prognostic Expression Signature
An international team documented TP53 mutation-related genomic changes across dozens of cancer types using data generated with five platforms for the Cancer Genome Atlas project.
Transcriptomics Reveals Tissue-Agnostic Features in Adenocarcinomas, Squamous Cell Carcinomas
A new analysis hints that adenocarcinomas or squamous cell carcinomas may have certain overlapping expression patterns, regardless of the tissue of origin.
Diverse Alterations Detected In Rare, Aggressive Uterine Cancer
An integrated analysis of uterine carcinosarcomas uncovered a range of somatic mutations and shifts in transcription, methylation, and microRNA expression.