Researchers have shown that metagenomic sequencing on the MinIon can identify the pathogen and antimicrobial resistance profile of UTIs in several hours.
Researchers are scouring samples for antibiotic resistance genes using sequencing, NBC News reports.
The test, called CloNeT, is based on a novel barcoding technology that links infecting bacteria to a database of antibiotic resistance profiles.
The goal is to develop a test that can identify the pathogen involved and predict antibiotic susceptibility within six hours of taking a urine sample.
The researchers are also developing the method in tandem with a more extensive pathogen profiling diagnostic platform from Swedish startup Q-linea.
The long-term goal of the project is to develop a single test for detecting an array of STDs and UTIs using Rheonix's fully automated point-of-care molecular diagnostic platform, called CARD.
The supplemental grant will be used to develop a point-of-care test for urinary tract infections.
Using metabolomics, American researchers have uncovered two iron-snatching siderophores whose production is ramped up in urinary tract infection-causing Escherichia coli strains compared to other gut E. coli.
In Nucleic Acids Research this week: ProTraits includes genetic, phenotypic data on bacteria, archaea; Candida albicans assembly 22; and more.
The Wall Street Journal reports that researchers are looking beyond Cas9 for CRISPR editing.
Familial DNA searches in criminal cases are winning over some critics, the Los Angeles Times reports.
In PNAS this week: miR-515 levels higher in women with preeclampsia, horizontal gene transfer in parasitic plants, and more.