ulcerative colitis | GenomeWeb

ulcerative colitis

A team of scientists and entrepreneurs is trying to build a company around a dataset from a large multi-omics clinical study funded by Genome Canada.

Researchers used genomic approaches to search for disease clues in purified cells from ileum or colon biopsies of pediatric inflammatory bowel disease patients.

IQuity's current tests analyze gene expression patterns detected in mRNA, but the firm is also exploring the diagnostic potential of long non-coding RNAs.

Researchers identified bacteria-infecting viruses transmitted from a healthy donor to children with ulcerative colitis during fecal transplantation.

The tools include activity-based protein probes and a metaproteomic database comprising all publicly available microbial protein and peptide sequences.

Through a meta-analysis of 10 pediatric-onset autoimmune diseases, Children's Hospital of Philadelphia researchers found 22 loci shared among the conditions.

The technology links distinctive genomic variants in bacteria of the human gut microbiome to two forms of inflammatory bowel disease.

In Genome Biology this week: investigation of host expression and microbial communities in pouchitis, liver fluke genome sequencing, and more.

A Washington University-led team detected differences in gut virus diversity in those with inflammatory bowel disease.

NEW YORK (GenomeWeb News) – The nonprofit Crohn's and Colitis Canada has awarded nearly C$800,000 (US$740,000) to fund three omics research projects that will investigate genes involved in inflammatory bowel diseases (IBD) and a possible method for treating such diseases.


In PNAS this week: miR-515 levels higher in women with preeclampsia, horizontal gene transfer in parasitic plants, and more.

A cancer researcher retracts 19 articles from one journal for image manipulation, according to Retraction Watch.

Precision medicine has to consider context in addition to genetic mutations in cancer treatment, Medscape reports.

Genomics may help the Cavendish banana from succumbing to fungal infections, a trio of researchers writes at the Conversation.