A team has identified disease loci for Crohn's and ulcerative colitis using fine mapping alongside high-density genotyping.
Based on genetic patterns in thousands of individuals with primary sclerosing cholangitis, researchers identified four new risk loci and explored ties to IBD.
A team of scientists and entrepreneurs is trying to build a company around a dataset from a large multi-omics clinical study funded by Genome Canada.
Researchers used genomic approaches to search for disease clues in purified cells from ileum or colon biopsies of pediatric inflammatory bowel disease patients.
IQuity's current tests analyze gene expression patterns detected in mRNA, but the firm is also exploring the diagnostic potential of long non-coding RNAs.
Researchers identified bacteria-infecting viruses transmitted from a healthy donor to children with ulcerative colitis during fecal transplantation.
The tools include activity-based protein probes and a metaproteomic database comprising all publicly available microbial protein and peptide sequences.
Through a meta-analysis of 10 pediatric-onset autoimmune diseases, Children's Hospital of Philadelphia researchers found 22 loci shared among the conditions.
The technology links distinctive genomic variants in bacteria of the human gut microbiome to two forms of inflammatory bowel disease.
In Genome Biology this week: investigation of host expression and microbial communities in pouchitis, liver fluke genome sequencing, and more.
Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.
By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.
Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.
In Nature this week: a Danish reference genome, and more.