ulcerative colitis Ulcerative Colitis Study Analyzes Gene Expression to Measure Risk of Progression to Surgery RNA data helped researchers develop a predicted polygenic transcriptional risk score that identified UC patients at fivefold elevated risk of colectomy. Inflammatory Bowel Disease Genetic Risk Architecture Appears Distinct in African Americans Using whole-genome sequence data for thousands of African American individuals, researchers teased out ancestry effects on polygenic risk of the conditions. Sano Genetics, Patients Know Best, BenevolentAI, C4X Discovery Form Ulcerative Colitis Alliance The British companies will collaborate on a database to support ulcerative colitis research and identify new drug targets for the disease. IBD Polygenic Risk Scores Improved With Data From Multiple Ancestral Backgrounds The researchers also examined the contribution of rare variants to inflammatory bowel disease to find a potential targetable pathway. Single-Cell Analysis Reveals Ulcerative Colitis Tissue, Immune Features With single-cell transcriptomic, T cell receptor, and B cell receptor data, researchers tracked immune shifts in tissue and peripheral blood samples from ulcerative colitis patients. Jul 21, 2020 Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations Jul 13, 2020 Genuity Science, Formerly WuXi NextCode, Reinvents Itself With US, Europe Focus Premium Mar 5, 2020 Genedata Moves Into R&D for Nonprofits, Adds Digital Pathology Support Premium Jan 21, 2020 PredictImmune Inks Multinational Commercialization Pact for IBD Test Dec 19, 2019 Scipher Medicine Closes Series B Funding Round Nov 7, 2019 PredictImmune, Crohn's & Colitis Foundation Collaborate on IBD Test Validation Study Oct 22, 2019 KSL Biomedical to Commercialize PredictImmune IBD Test in North America Sep 19, 2019 PredictImmune Expands Licensing Deal With Cambridge Enterprise Jul 9, 2019 Celsius Therapeutics, Janssen Biotech Form Biomarker Discovery Alliance Apr 2, 2019 PredictImmune, Addenbrooke's Hospital Sign Agreement to Provide IBD Diagnostic in UK, Ireland Mar 6, 2019 Inflammatory Bowel Disease Transcriptome Analysis Finds Increased Levels of SERPINE1 Jan 9, 2019 Scipher Medicine Builds Evidence for Tests Predicting Response to Autoimmune Disease Drugs Premium Dec 13, 2018 PredictImmune Wins £100K Grant for Study of IBD Prognostic Dec 11, 2018 PredictImmune Gains CE-IVD Mark for IBD Test Sep 18, 2018 Prescient Medicine, Metabiomics Form GI Dx Partnership May 4, 2018 PredictImmune Plans 2019 European, US Launches for qPCR-Based Crohn's Biomarker Test Premium Aug 23, 2017 IBM, Broad Institute to Map Human Microbiome on World Community Grid Jun 28, 2017 Genotyping, Fine Mapping Identifies Single-Variant Resolution Loci for IBD Dec 19, 2016 Liver Disease GWAS Highlights Genetic Overlap With, Differences From IBD Jun 10, 2016 Canadian Startup Biotagenics Plans to Monetize IBD Dataset Premium Load More Breaking News SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes People in the News: New Appointments at Myriad Genetics, Becton Dickinson, Delfi Diagnostics, More In Brief This Week: Virginia Commonwealth University, Dovetail Genomics, Lucid Diagnostics, and More New Products Posted to GenomeWeb: Bio-Rad, PerkinElmer, Ares Genetics, Purigen Biosystems, More Genetron Health, Fosun Ink Commercialization Deal for Seq-MRD Test in China MultiMuTHER Team Tracks Expression, Metabolite Relationships in Aging TwinsUK Participants The Scan More Boosters for US Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes. From a Pig A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports. For Privacy's Sake Wired reports that more US states are passing genetic privacy laws. Science Paper on How Poaching Drove Evolution in African Elephants In Science this week: poaching has led to the rapid evolution of tuskless African elephants.